Description

(+)-Vinylboronic Acid Pinanediol Ester is a high-purity, chiral organoboron reagent essential for advanced organic synthesis. This compound matters as a critical building block for constructing complex molecules with precise stereochemistry, enabling the development of novel pharmaceuticals and agrochemicals. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling and other transition-metal-catalyzed reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for introducing vinyl groups with defined stereochemistry.
• Agrochemical Research & Development: Used in creating novel, stereochemically-defined pesticides and herbicides with potentially enhanced efficacy and selectivity.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile vinyl boronate ester coupling partner for forming carbon-carbon bonds with aryl and vinyl halides under palladium catalysis.
• Materials Science & Polymer Chemistry: Employed in the synthesis of functionalized monomers and advanced polymers with specific optical or electronic properties.
• Asymmetric Synthesis & Catalysis: Utilized in stereoselective transformations to create enantiomerically enriched compounds for fine chemical production.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new reaction pathways in synthetic organic chemistry laboratories.

Basic Information

Item	Details
Product Name	(+)-Vinylboronic Acid Pinanediol Ester
CAS No.	132488-71-2
Molecular Formula	C₁₂H₁₉BO₂
Molecular Weight	206.09 g/mol
Synonyms	(+)-Vinylpinacolborane; (1R,2S,3R,5S)-(-)-2-(Vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (1R,2S,3R,5S)-Pinanediol Vinylboronate; (R)-(-)-2-(Vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Vinylboronic Acid Pinanediol Ester, (+)-; Vinyl Pinanediol Boronic Ester; (1R)-(-)-Pinanediol Vinylboronate
EINECS	Contact for details

Quality Control

Our (+)-Vinylboronic Acid Pinanediol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.