Description

2-Bromo-1-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Ethan-1-One is a high-value, specialized brominated ketone intermediate with a unique tetralin-derived structure. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical and material science research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized aromatic ketone motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring a rigid, lipophilic scaffold.
• Agrochemical Research: Used in developing new generation pesticides and herbicides where the tetramethyl-tetrahydronaphthalene moiety can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and liquid crystals with specific optical or thermal properties.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to construct more complex molecular architectures.
• Chemical Biology Probe Development: Employed in creating tagged or photoaffinity probes for studying protein-ligand interactions and biological pathways.
• Fragrance & Flavor Intermediate: Potential use in the synthesis of high-value aroma chemicals with musk or amber characteristics derived from its tetralin core.

Basic Information

Product Name	2-Bromo-1-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Ethan-1-One
CAS No.	132392-28-0
Molecular Formula	C₁₈H₂₃BrO
Molecular Weight	335.28 g/mol
Synonyms	2-Bromo-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone; 2-Bromo-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthyl)ethan-1-one; 2-Bromo-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthyl)ethanone; 2'-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-acetonaphthone; 2-Bromo-2'-aceto-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene; TTN Bromo Ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Ethan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under amber light or in light-protected containers to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.