Description

1-Pentanone, 2,2-Difluoro-3-Hydroxy-1-Phenyl- (9Ci) is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine atoms and a phenyl group, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly those requiring fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the difluoro and phenyl functionalities can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers or polymers where fluorine incorporation can alter surface properties and chemical resistance.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring new fluorination reactions and the effects of fluorine substitution.

Basic Information

Product Name	1-Pentanone, 2,2-Difluoro-3-Hydroxy-1-Phenyl- (9Ci)
CAS No.	132365-90-3
Molecular Formula	C11H12F2O2
Molecular Weight	214.21 g/mol
Synonyms	2,2-Difluoro-3-hydroxy-1-phenylpentan-1-one; 1-Phenyl-2,2-difluoro-3-hydroxypentan-1-one; 3-Hydroxy-2,2-difluoro-1-phenyl-1-pentanone; α,α-Difluoro-β-hydroxy-1-phenyl-1-pentanone; 132365-90-3 (CAS); Difluorohydroxyphenylpentanone
EINECS	Contact for details

Quality Control

Our 1-Pentanone, 2,2-Difluoro-3-Hydroxy-1-Phenyl- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.