Description

1-Propanone, 1-(4-Aminophenyl)-2-Chloro-, (R)- (9Ci) is a chiral, optically active organic compound featuring a propanone backbone substituted with an aminophenyl group and a chlorine atom. This specific stereochemistry and functional group combination make it a valuable chiral building block and intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries. The compound's structure is integral to the synthesis of complex molecules where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological or metabolic pathways.
• Asymmetric Synthesis: Utilized as a precursor or catalyst ligand in stereoselective reactions to construct complex molecules with high enantiomeric purity.
• Agrochemical Research: Acts as a building block for developing novel, chiral herbicides, fungicides, or plant growth regulators with enhanced specificity.
• Material Science: Investigated for the synthesis of specialty polymers or liquid crystals where the chiral center influences material properties.
• Academic & Industrial R&D: Used in chemical research laboratories for methodological studies and the discovery of new synthetic routes.

Basic Information

Product Name	1-Propanone, 1-(4-Aminophenyl)-2-Chloro-, (R)- (9Ci)
CAS No.	132298-11-4
Molecular Formula	C9H10ClNO
Molecular Weight	183.63 g/mol
Synonyms	(R)-1-(4-Aminophenyl)-2-chloropropan-1-one; (R)-2-Chloro-1-(4-aminophenyl)propan-1-one; 1-Propanone, 1-(4-aminophenyl)-2-chloro-, (R)-; (R)-α-Chloro-4-aminopropiophenone; (R)-2-Chloro-1-(4-aminophenyl)-1-propanone; (R)-2-Chloro-4'-aminopropiophenone; (R)-p-Amino-α-chloropropiophenone; (R)-4-Amino-2-chloropropiophenone
EINECS	Contact for details

Quality Control

Our production of 1-Propanone, 1-(4-Aminophenyl)-2-Chloro-, (R)- (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC, Chiral GC), identity confirmation (IR, NMR), and quantification of related substances to ensure it meets exacting research and process development standards. A detailed Certificate of Analysis (COA) specifying purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.