Description

Cyclopropanecarboxaldehyde, 2-(4-Methylphenyl)-, trans- (9Ci) is a specialized chiral aldehyde building block featuring a cyclopropane ring and a p-tolyl substituent. This compound matters as a high-value intermediate for synthesizing complex molecules with defined stereochemistry, enabling the development of novel active ingredients. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating new drug candidates, crop protection agents, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the cyclopropane moiety can impart unique biological activity and stability.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific optical or mechanical properties.

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 2-(4-Methylphenyl)-, trans- (9Ci)
CAS No.	132145-62-1
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	trans-2-(p-Tolyl)cyclopropanecarboxaldehyde; (1R,2S)-2-(4-Methylphenyl)cyclopropanecarbaldehyde; (1S,2R)-2-(4-Methylphenyl)cyclopropanecarbaldehyde; 2-(4-Methylphenyl)cyclopropanecarboxaldehyde, trans-; p-Methyl-trans-2-formylcyclopropylbenzene; 2-(p-Tolyl)cyclopropanecarbaldehyde; trans-2-(4-Methylphenyl)-1-cyclopropanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxaldehyde, 2-(4-Methylphenyl)-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, keep away from oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.