Description

2-Fluorodexetimide is a specialized fluorinated organic compound, identified by CAS NO 131948-18-0, that serves as a critical intermediate in advanced pharmaceutical synthesis and fine chemical research. Its value lies in the introduction of a fluorine atom, a key strategy in modern medicinal chemistry for modulating the bioavailability, metabolic stability, and binding affinity of target molecules. This high-purity building block is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors seeking to innovate new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-cholinergic drug candidates.
• Medicinal Chemistry Research: Used as a fluorinated building block to study structure-activity relationships (SAR) and to improve the pharmacokinetic profiles of lead compounds.
• Agrochemical Synthesis: Serves as an intermediate in the development of new-generation pesticides and herbicides, where fluorine incorporation enhances biological activity.
• Biochemical Tool Compound: Employed in pharmacological studies to investigate specific receptor interactions and enzyme inhibition mechanisms.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, fluorinated specialty chemicals.

Basic Information

Product Name	2-Fluorodexetimide
CAS No.	131948-18-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dexetimide, 2-Fluoro-; 2-Fluoro Dexetimide; (3R)-1-(2-Fluorophenyl)-3-piperidin-1-yl-1H-isoindole; (R)-1-(2-Fluorophenyl)-3-(piperidin-1-yl)isoindoline; 131948-18-0; UNII-8VJ54932H5; 8VJ54932H5
EINECS	Contact for details

Quality Control

Our 2-Fluorodexetimide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.