Description

(R)-2-Benzylmorpholine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its well-defined stereochemistry, which is critical for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced materials. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and receptor modulators.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and pesticides where specific stereochemistry impacts biological activity.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring the (R)-2-benzylmorpholine scaffold.
• Academic & Process R&D: A valuable reference standard and starting material for method development and scaling studies in academic and industrial laboratories.

Basic Information

Product Name	(R)-2-Benzylmorpholine Hydrochloride
CAS No.	131887-53-1
Molecular Formula	C11H15NO • HCl
Molecular Weight	213.70 g/mol
Synonyms	(R)-2-Benzylmorpholine HCl; (R)-2-(Phenylmethyl)morpholine hydrochloride; (R)-2-Benzylmorpholine monohydrochloride; (R)-N-Benzylmorpholine-2-carboxamide hydrochloride (related); (2R)-2-Benzylmorpholine hydrochloride; Morpholine, 2-(phenylmethyl)-, (2R)-, hydrochloride; (R)-2-Benzylmorpholine Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our (R)-2-Benzylmorpholine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.