Description

Decarboxy Enrofloxacin is a key pharmaceutical intermediate and metabolite of the broad-spectrum fluoroquinolone antibiotic, enrofloxacin. This compound is critical for analytical research, quality control, and the development of veterinary and human pharmaceuticals. It is primarily utilized by research institutions, analytical laboratories, and manufacturers in the pharmaceutical and animal health sectors for method development, impurity profiling, and reference standard applications.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the identification and quantification of enrofloxacin and its related substances in drug products and raw materials.
• Metabolite Studies: Used in pharmacokinetic and metabolic pathway research to study the behavior and degradation of enrofloxacin in biological systems.
• Impurity Profiling: Essential for quality control laboratories to identify, monitor, and control the level of this specific degradation product in active pharmaceutical ingredients (APIs) and finished formulations.
• Method Development & Validation: Employed in the development and validation of analytical methods, particularly High-Performance Liquid Chromatography (HPLC) and LC-MS/MS, for antibiotic analysis.
• Veterinary Drug Research: Supports research and development of new antibacterial agents and formulations within the animal health industry.
• Regulatory Compliance Testing: Aids in testing to meet stringent pharmacopoeial standards (e.g., USP, EP) for antibiotic purity and safety.

Basic Information

Product Name	Decarboxy Enrofloxacin
CAS No.	131775-99-0
Molecular Formula	C18H20FN3O3
Molecular Weight	345.37 g/mol
Synonyms	1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid (Decarboxylated Form); Enrofloxacin Impurity C; Enrofloxacin Decarboxylated; Enrofloxacin Related Compound C; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid Decarboxy Derivative; Bay Vp 2674 Decarboxy; Decarboxy Enrofloxacin Hydrochloride (if applicable)
EINECS	Contact for details

Quality Control

Our Decarboxy Enrofloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets high-purity standards suitable for research and analytical use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.