Description

2-(4-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol is a versatile fluorinated organic building block characterized by a central neopentyl glycol core substituted with a fluorophenyl group. This compound matters for its unique structure, which combines the stability of a fluorinated aromatic ring with the reactivity of multiple hydroxyl groups, making it a valuable intermediate in advanced synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for specialty polymers, including polyesters and polyurethanes, imparting specific thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex, fluorinated molecular architectures.
• Material Science Research: Investigated for use in organic electronic materials and as a component in advanced coatings.

Basic Information

Product Name	2-(4-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol
CAS No.	131506-01-9
Molecular Formula	C10H13FO3
Molecular Weight	200.21 g/mol
Synonyms	2-(4-Fluorophenyl)-2-(hydroxymethyl)-1,3-propanediol; 4-Fluoro-alpha,α-bis(hydroxymethyl)benzenemethanol; 2-(4-Fluorophenyl)-2-(hydroxymethyl)propane-1,3-diol; 1,3-Propanediol, 2-(4-fluorophenyl)-2-(hydroxymethyl)-; 4-Fluorobenzylidenebis(trimethylene alcohol); p-Fluorobenzylidenebis(trimethylene alcohol); (4-Fluorophenyl)bis(hydroxymethyl)methanol; Fluorophenyl neopentyl glycol derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect product quality. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.