Description

2,6,7-Trioxabicyclo(2.2.2)Octane, 1-(4-Ethynylphenyl)-4-(2-Fluoropheny L)- is a specialized bicyclic orthoester derivative, a high-value intermediate prized for its unique molecular architecture. This compound matters for its role in advanced material science and pharmaceutical research, where its rigid, oxygen-rich scaffold and functionalized aromatic rings enable precise molecular design. It is primarily needed by R&D chemists and process development teams in the fields of organic electronics, polymer chemistry, and medicinal chemistry for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Advanced Polymer Monomer: Used in the development of high-performance, cross-linked polymers and resins with enhanced thermal and chemical stability for specialty coatings and composites.
• Organic Electronic Materials: Acts as a precursor for materials used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs) due to its conjugated ethynylphenyl group.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial Research: A valuable tool for synthetic methodology development and exploring new chemical spaces in both university and corporate R&D laboratories.

Basic Information

Product Name	2,6,7-Trioxabicyclo(2.2.2)Octane, 1-(4-Ethynylphenyl)-4-(2-Fluoropheny L)-
CAS No.	131505-64-1
Molecular Formula	C18H15FO3
Molecular Weight	298.31 g/mol
Synonyms	1-(4-Ethynylphenyl)-4-(2-fluorophenyl)-2,6,7-trioxabicyclo[2.2.2]octane; 2,6,7-Trioxabicyclo[2.2.2]octane, 1-(4-ethynylphenyl)-4-(2-fluorophenyl)-; 1-(4-Ethynylphenyl)-4-(o-fluorophenyl)-2,6,7-trioxabicyclo[2.2.2]octane; Fluorinated Bicyclic Orthoester; Bicyclic Orthoester Derivative; CAS 131505-64-1
EINECS	Contact for details

Quality Control

Our 2,6,7-Trioxabicyclo(2.2.2)Octane, 1-(4-Ethynylphenyl)-4-(2-Fluoropheny L)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to traceability and documentation supports your regulatory and quality assurance requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or direct light should be avoided. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.