Description

Oxiranemethanol, 3-(2-Pentynyl)-, trans- (9Ci) is a specialized alkyne-functionalized oxirane derivative, a high-value building block in synthetic organic chemistry. Its core value lies in the unique reactivity conferred by the combination of an epoxide ring and a terminal alkyne group, enabling precise and efficient construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors who require sophisticated intermediates for drug discovery and polymer synthesis. Its defined stereochemistry (trans-) ensures consistent and predictable reaction outcomes in critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring alkyne "click chemistry" handles or epoxide ring-opening for functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where its bifunctional nature allows for the creation of targeted bioactive molecules.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, coatings, and resins with tailored properties such as enhanced adhesion, chemical resistance, or thermal stability.
• Liquid Crystal & OLED Materials: Employed in the synthesis of advanced organic electronic materials, where its rigid, linear structure and functional groups contribute to desired optical and electronic characteristics.
• Chemical Biology Probes: Utilized in the development of molecular probes and bioconjugation reagents, leveraging the alkyne group for bioorthogonal labeling strategies.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, catalysis research, and exploring new reaction manifolds involving strained heterocycles.

Basic Information

Product Name	Oxiranemethanol, 3-(2-Pentynyl)-, trans- (9Ci)
CAS No.	131321-18-1
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	trans-3-(2-Pentynyl)oxiranemethanol; 2-[(2-Pentyn-1-yl)oxiranyl]methanol; 3-(Pent-2-yn-1-yl)oxiran-2-ylmethanol; Glycidol, 3-(2-pentynyl)-, trans-; Oxirane-2-methanol, 3-(2-pentynyl)-, (2R,3S)-rel-; (trans)-3-(2-Pentynyl)glycidol; A functionalized glycidol derivative.
EINECS	Contact for details

Quality Control

Every batch of Oxiranemethanol, 3-(2-Pentynyl)-, trans- (9Ci) is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. We employ advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy for comprehensive characterization. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for pharmaceutical applications, and we offer the capability to produce material meeting USP/EP monograph requirements for critical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be opaque or kept in dark conditions. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.