Description

Cyclopropanecarboxylic Acid, 2,2-Difluoro-3,3-Dimethyl- (9Ci) is a high-purity fluorinated cyclopropane derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique difluorocyclopropane structure offers significant value for modulating the physicochemical properties and metabolic stability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex, high-value active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluorocyclopropane moiety can enhance biological activity and environmental stability.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with tailored properties, such as improved thermal stability or specific optical characteristics.
• Fluorine Chemistry & Catalysis: Serves as a valuable substrate or ligand precursor in organometallic chemistry and catalytic reaction development, leveraging its fluorine atoms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis providers and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2,2-Difluoro-3,3-Dimethyl- (9Ci)
CAS No.	131262-35-6
Molecular Formula	C6H8F2O2
Molecular Weight	150.12 g/mol
Synonyms	2,2-Difluoro-3,3-dimethylcyclopropanecarboxylic acid; 3,3-Dimethyl-2,2-difluorocyclopropanecarboxylic Acid; 2,2-Difluoro-3,3-dimethylcyclopropane-1-carboxylic acid; 1-Cyclopropanecarboxylic acid, 2,2-difluoro-3,3-dimethyl-; Difluorodimethylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2,2-Difluoro-3,3-Dimethyl- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood or well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.