Description

(S)-Tetrahydro-1,3,3-Triphenyl-1H,3H-Pyrrolo[1,2-C][1,3,2]Oxaborole, 99% (S)-Phenyl Oxazaborolidine is a high-purity, chiral organoboron compound that serves as a highly effective catalyst for enantioselective synthesis. Its value lies in enabling the production of single-enantiomer intermediates and active pharmaceutical ingredients (APIs) with exceptional stereochemical control. This product is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and efficient asymmetric transformations.

Application

• Asymmetric Reduction Catalyst: A key catalyst for the enantioselective reduction of prochiral ketones to chiral secondary alcohols, a fundamental reaction in chiral molecule synthesis.
• Pharmaceutical Intermediate Synthesis: Critical for the production of enantiomerically pure intermediates used in the manufacture of chiral drugs, including β-blockers, antidepressants, and antifungal agents.
• Agrochemical Production: Used in the synthesis of chiral active ingredients for herbicides, fungicides, and insecticides where specific stereochemistry is required for optimal biological activity.
• Fine Chemical and Fragrance Manufacturing: Enables the creation of chiral flavor and fragrance compounds with defined organoleptic properties.
• Academic and Process R&D: A valuable tool for method development and scaling up enantioselective reactions in academic and industrial research settings.
• Catalyst Screening and Optimization: Serves as a benchmark or lead compound in the development of new chiral catalysts and ligand systems.

Basic Information

Item	Details
Product Name	(S)-Tetrahydro-1,3,3-Triphenyl-1H,3H-Pyrrolo[1,2-C][1,3,2]Oxaborole, 99% (S)-Phenyl Oxazaborolidine
CAS No.	131180-90-0
Molecular Formula	C24H23BNO
Molecular Weight	352.26 g/mol
Synonyms	(S)-(-)-2-Methyl-CBS-oxazaborolidine; (S)-CBS Catalyst; (S)-Corey-Bakshi-Shibata Catalyst; (S)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxaborole; (S)-3,3-Diphenyl-1-methyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxaborole; (S)-Oxazaborolidine Catalyst; (S)-Phenyl Oxazaborolidine; CBS Reagent
EINECS	Contact for details

Quality Control

Our (S)-Phenyl Oxazaborolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is tested to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing assay (by HPLC), chiral purity, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed and allowed to equilibrate to room temperature before opening to prevent condensation and degradation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.