Description

α-(1,1,-Difluoroethyl)-α-Methyl-γ-Butyrolactone is a high-value, fluorinated lactone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a difluoroethyl group, makes it a critical precursor for introducing fluorine atoms into complex molecules, thereby modifying their physical, chemical, and biological properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), potentially enhancing metabolic stability and bioavailability.
• Agrochemical Research: Used in creating novel fluorinated herbicides, fungicides, and insecticides, where fluorine can improve efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for specialty polymers and advanced materials with tailored surface properties and stability.
• Fluorine Chemistry Research: An essential reagent in methodological studies for developing new fluorination and C-F bond functionalization reactions.
• Liquid Crystal & Electronic Chemicals: Potential use in the synthesis of fluorinated components for display technologies and electronic materials.

Basic Information

Product Name	α-(1,1,-Difluoroethyl)-α-Methyl-γ-Butyrolactone
CAS No.	131147-39-2
Molecular Formula	C9H14F2O2
Molecular Weight	192.20 g/mol
Synonyms	α-(1,1-Difluoroethyl)-α-methyl-γ-butyrolactone; 2-(1,1-Difluoroethyl)-2-methylbutyrolactone; 4,4-Difluoro-3-methyl-3-pentanolide; 3-Methyl-3-(1,1-difluoroethyl)dihydro-2(3H)-furanone; 2-Methyl-2-(1,1-difluoroethyl)-γ-butyrolactone; DFEMBL (abbreviation); Fluorinated lactone building block
EINECS	Contact for details

Quality Control

Every batch of α-(1,1,-Difluoroethyl)-α-Methyl-γ-Butyrolactone is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.