Description

3-(4-Carboxybenzoyl)-2-Quinolinecarboxaldehyde is a specialized quinoline derivative that serves as a key synthetic intermediate and analytical reagent. Its bifunctional structure, featuring both a reactive aldehyde and a carboxylic acid group, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for applications ranging from chemical synthesis to fluorescence labeling.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those with quinoline-based pharmacophores for anti-malarial, anti-cancer, or anti-inflammatory activity.
• Fluorescent Probe Synthesis: Acts as a precursor for developing sensitive fluorescent tags and sensors used in bioimaging and diagnostic assays.
• Ligand and Chelator Preparation: Employed to create complexing agents for metal ions in catalysis or metal recovery processes.
• Polymer and Material Science: Serves as a monomer or cross-linking agent for synthesizing functional polymers with specific optical or chemical properties.
• Organic Synthesis Building Block: Utilized in multi-step organic reactions, including condensation and coupling reactions, to introduce both aldehyde and acid functionalities.
• Analytical Chemistry Reagent: Functions as a derivatization agent for the detection and quantification of amines and other nucleophiles via HPLC or spectroscopy.

Basic Information

Product Name	3-(4-Carboxybenzoyl)-2-Quinolinecarboxaldehyde
CAS No.	131124-59-9
Molecular Formula	C18H11NO4
Molecular Weight	305.29 g/mol
Synonyms	2-Quinolinecarboxaldehyde, 3-(4-carboxybenzoyl)-; 3-(4-Carboxybenzoyl)quinoline-2-carboxaldehyde; 4-(2-Formylquinolin-3-ylcarbonyl)benzoic acid; CBQCA (common abbreviation); 3-(4-Carboxybenzoyl)-2-quinolinecarbaldehyde; 3-(p-Carboxybenzoyl)-2-quinolinecarboxaldehyde; 4-[(2-Formyl-3-quinolyl)carbonyl]benzoic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Carboxybenzoyl)-2-Quinolinecarboxaldehyde is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.