Description

Benz(3,4)-6-Oxaestra-1,3,5(10),8-Tetraen-17-Ol is a high-purity steroidal intermediate of significant interest in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of novel therapeutic agents, offering researchers a reliable and well-characterized starting material. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries focused on steroid-based drug discovery and process development. CAS No. 131077-42-4.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and new drug candidate development.
• Process Chemistry: Serves as a defined starting material for scaling up synthetic routes in pilot plants and commercial manufacturing.
• Reference Standard: Employed as an analytical standard for quality control and method validation in HPLC and GC analyses.
• Fine Chemical Synthesis: Utilized in the preparation of specialized steroidal compounds for biochemical research.

Basic Information

Product Name	Benz(3,4)-6-Oxaestra-1,3,5(10),8-Tetraen-17-Ol
CAS No.	131077-42-4
Molecular Formula	C₁₈H₂₂O₂
Molecular Weight	270.37 g/mol
Synonyms	6-Oxaestra-1,3,5(10),8-tetraen-17-ol, benzo(3,4) derivative; 17-Hydroxy-6-oxaestra-1,3,5(10),8-tetraene; 6-Oxaestra-1,3,5(10),8-tetraen-17β-ol; Benz(3,4)-6-oxaestra-1,3,5(10),8-tetraen-17β-ol; 6-Oxa-1,3,5(10),8-estratetraen-17-ol; Steroid 6-oxa tetraene intermediate; 131077-42-4 (CAS Name base).
EINECS	Contact for details

Quality Control

Our Benz(3,4)-6-Oxaestra-1,3,5(10),8-Tetraen-17-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.