Description

5-(Chloromethyl)Thiazole Hydrochloride is a versatile and reactive heterocyclic building block essential for advanced organic synthesis. Its bifunctional nature, featuring both a chloromethyl group and a thiazole ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, antibacterial, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the development of modern pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiazole moiety.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and mechanisms.
• Custom Synthesis Building Block: A high-value reagent for contract research organizations (CROs) and custom synthesis houses working on proprietary compounds.

Basic Information

Product Name	5-(Chloromethyl)Thiazole Hydrochloride
CAS No.	131052-44-3
Molecular Formula	C4H5Cl2NS
Molecular Weight	178.06 g/mol
Synonyms	5-(Chloromethyl)-1,3-thiazole hydrochloride; Thiazole, 5-(chloromethyl)-, hydrochloride; 5-Chloromethylthiazole hydrochloride; 1,3-Thiazole, 5-(chloromethyl)-, hydrochloride; (Chloromethyl)thiazole hydrochloride
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)Thiazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.