Description

(1R,2S)-2-(tert-Butoxycarbonylamino)Cyclopentanecarboxylic Acid is a high-purity, chiral building block of significant importance in modern synthetic chemistry. Its core value lies in providing a stereochemically defined scaffold for constructing complex molecules, which is critical for ensuring the efficacy and safety of final products. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and other small-molecule therapeutic development.
• Peptide Mimetics & Conformationally Restricted Peptides: Used to introduce constrained cyclopentane backbones, enhancing metabolic stability and biological activity.
• Agrochemical Research: Serves as a building block for creating chiral active ingredients with specific modes of action.
• Asymmetric Synthesis Catalyst Ligand Precursor: Utilized in the preparation of chiral ligands for metal-catalyzed asymmetric transformations.
• Academic & Process Chemistry Research: Employed in method development and scaling up synthetic routes for complex organic molecules.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom production of advanced intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	(1R,2S)-2-(tert-Butoxycarbonylamino)Cyclopentanecarboxylic Acid
CAS No.	130981-12-3
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	(1R,2S)-2-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid; (1R,2S)-2-(Boc-amino)cyclopentanecarboxylic acid; Boc-(1R,2S)-2-aminocyclopentanecarboxylic acid; (1R,2S)-2-((tert-Butoxycarbonyl)amino)cyclopentane-1-carboxylic acid; (1R,2S)-Boc-Acp-OH; (1R,2S)-N-Boc-2-aminocyclopentanecarboxylic acid; trans-(1R,2S)-2-(Boc-amino)cyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]amino]-, (1R,2S)-
EINECS	Contact for details

Quality Control

Our (1R,2S)-2-(tert-Butoxycarbonylamino)Cyclopentanecarboxylic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.