Description

Ethanone, 2,2,2-Trifluoro-1-(2-Phenylcyclopropyl)-, (1S-Cis)- (9Ci) is a high-purity chiral trifluoromethyl ketone derivative, identified by CAS number 130980-01-7. This compound is a critical synthetic intermediate valued for its ability to introduce the trifluoromethyl group and a defined stereocenter into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique structural features can impart desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Asymmetric Synthesis: Serves as a versatile electrophile or precursor in stereoselective reactions, including nucleophilic additions and cyclizations, for constructing complex chiral molecules.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique optical or surface properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on incorporating fluorine atoms into organic molecules to modulate their physical and chemical properties.

Basic Information

Item	Detail
Product Name	Ethanone, 2,2,2-Trifluoro-1-(2-Phenylcyclopropyl)-, (1S-Cis)- (9Ci)
CAS No.	130980-01-7
Molecular Formula	C11H9F3O
Molecular Weight	214.18 g/mol
Synonyms	(1S-cis)-2,2,2-Trifluoro-1-(2-phenylcyclopropyl)ethanone; (1S,2S)-2,2,2-Trifluoro-1-(2-phenylcyclopropyl)ethan-1-one; (1S,2S)-2,2,2-Trifluoro-1-(2-phenylcyclopropyl)ethanone; 2,2,2-Trifluoro-1-[(1S,2S)-2-phenylcyclopropyl]ethanone; (1S,2S)-2-Phenylcyclopropyl trifluoromethyl ketone; (1S-cis)-2,2,2-Trifluoro-1-(2-phenylcyclopropyl)ethan-1-one; Trifluoromethyl (1S,2S)-2-phenylcyclopropyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(2-Phenylcyclopropyl)-, (1S-Cis)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.