Description

4-Hydroxy-3-Methoxycinnamaldehyde, Trimethylsilyl Derivative is a chemically modified, silylated derivative of ferulic acid aldehyde, designed to enhance stability and reactivity for advanced synthetic applications. This compound is crucial for researchers and manufacturers requiring a protected phenolic group to prevent unwanted side reactions during complex organic syntheses. It serves as a key synthetic intermediate and analytical standard in the development of pharmaceuticals, agrochemicals, and fine chemicals for the global market.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting inflammation and neurological disorders, where the trimethylsilyl group acts as a protecting group.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex molecular architectures in medicinal chemistry and material science research.
• Analytical Reference Standard: Employed in HPLC, GC-MS, and NMR for the qualitative and quantitative analysis of related cinnamaldehyde derivatives in quality control laboratories.
• Agrochemical Research: Investigated as an intermediate for developing new plant growth regulators or bioactive compounds with enhanced stability profiles.
• Flavor & Fragrance Chemistry: Used in the research and development of stabilized derivatives of natural aroma compounds for high-value applications.
• Material Science Precursor: Explored in the synthesis of specialized polymers or organic electronic materials where controlled functional group manipulation is required.

Basic Information

Product Name	4-Hydroxy-3-Methoxycinnamaldehyde, Trimethylsilyl Derivative
CAS No.	130878-30-7
Molecular Formula	C13H18O3Si
Molecular Weight	250.37 g/mol
Synonyms	Ferulaldehyde TMS Derivative; (E)-3-(4-((Trimethylsilyl)oxy)-3-methoxyphenyl)acrylaldehyde; 4-(Trimethylsilyloxy)-3-methoxycinnamaldehyde; Coniferyl aldehyde TMS ether; TMS-Ferulaldehyde; 3-Methoxy-4-trimethylsilyloxycinnamaldehyde; 4-OTMS-3-OMe Cinnamaldehyde
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Methoxycinnamaldehyde, Trimethylsilyl Derivative is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.