Description

2-Propanone, 1-Fluoro-1-(4-Fluorophenyl)- is a specialized fluorinated ketone building block with the CAS registry number 130754-16-4. This compound is valued for its unique molecular structure, which incorporates two fluorine atoms, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides where the fluorine moiety enhances biological activity and stability.
• Material Science Research: Serves as a precursor for fluorinated polymers and advanced organic electronic materials.
• Organic Synthesis: A versatile reagent for introducing fluorinated phenyl ketone groups into complex molecular architectures in medicinal and process chemistry.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Propanone, 1-Fluoro-1-(4-Fluorophenyl)-
CAS No.	130754-16-4
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(4-Fluorophenyl)-1-fluoroacetone; 4-Fluoro-α-fluorophenylacetone; 1-Fluoro-1-(4-fluorophenyl)propan-2-one; 4-Fluorobenzoyl fluoride, dimethyl acetal (related precursor); α-Fluoro-4-fluoroacetophenone; p-Fluorophenyl fluoromethyl ketone
EINECS	Contact for details

Quality Control

Every batch of 2-Propanone, 1-Fluoro-1-(4-Fluorophenyl)- is produced and tested under a strict quality management system. We ensure high purity and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.