Description

4-Amino-2,2-difluorobutyric acid is a fluorinated amino acid derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both amino and difluoro functional groups, makes it a valuable intermediate for creating molecules with enhanced biological activity and metabolic stability. This compound is primarily utilized by research institutions and pharmaceutical companies in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of fluorinated drug candidates, including protease inhibitors and enzyme modulators.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the difluoro moiety can improve efficacy and environmental profile.
• Peptidomimetics & Bioactive Molecules: Serves as a non-natural amino acid analog for constructing peptides with improved stability against enzymatic degradation.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty chemicals with unique surface properties.
• Chemical Biology Probes: Useful for incorporating fluorine atoms into molecular probes for imaging and mechanistic studies.

Basic Information

Product Name	4-Amino-2,2-difluorobutyric Acid
CAS No.	130592-02-8
Molecular Formula	C₄H₇F₂NO₂
Molecular Weight	139.10 g/mol
Synonyms	2,2-Difluoro-4-aminobutanoic Acid; 4-Amino-2,2-difluorobutanoic Acid; DL-4-Amino-2,2-difluorobutyric Acid; (RS)-4-Amino-2,2-difluorobutyric Acid; 4-Amino-2,2-difluoro-butanoic acid; 130592-02-8; Butanoic acid, 4-amino-2,2-difluoro-
EINECS	Contact for details

Quality Control

Our 4-Amino-2,2-difluorobutyric acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.