Description

(2R,3R)-(+)-2,3-Epoxy-2-Methyl-3-Phenyl-1-Propanol is a high-purity chiral epoxide building block of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a critical intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity and environmental safety.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in the development and testing of new chiral catalysts and methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & R&D: A valuable tool in academic laboratories for studying epoxide ring-opening reactions and stereoselective transformations.

Basic Information

Product Name	(2R,3R)-(+)-2,3-Epoxy-2-Methyl-3-Phenyl-1-Propanol
CAS No.	130550-48-0
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(2R,3R)-2-Methyl-3-phenyloxiranemethanol; (+)-(2R,3R)-2,3-Epoxy-2-methyl-3-phenyl-1-propanol; (2R,3R)-2-(Hydroxymethyl)-2-methyl-3-phenyloxirane; (2R,3R)-1,2-Epoxy-1-methyl-2-phenyl-3-propanol; trans-2,3-Epoxy-2-methyl-3-phenylpropan-1-ol; Chiral Styrene Oxide Derivative
EINECS	Contact for details

Quality Control

Our (2R,3R)-(+)-2,3-Epoxy-2-Methyl-3-Phenyl-1-Propanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full specification data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.