Description

5,6-Epoxy5,6,7,8-Tetrahydroquinoline is a specialized heterocyclic building block and epoxide intermediate of significant interest in advanced organic synthesis. Its unique fused-ring structure containing both an epoxide and a partially saturated quinoline moiety makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel quinoline-based drug candidates, potentially targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for creating new pesticides, herbicides, or fungicides with enhanced activity and selectivity.
• Material Science Research: Used in the development of advanced organic materials, including ligands for catalysis, photoactive compounds, or components for organic electronics.
• Chemical Biology Probe Development: Employed as a scaffold for creating molecular probes to study enzyme function or biological pathways due to its reactive epoxide group.
• Academic & Industrial R&D: Essential for methodological studies in organic chemistry, particularly in ring-opening reactions and heterocycle functionalization.
• Fine Chemical Production: Acts as a precursor for the manufacture of other high-value, complex specialty chemicals.

Basic Information

Product Name	5,6-Epoxy5,6,7,8-Tetrahydroquinoline
CAS No.	130536-45-7
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	5,6-Epoxy-5,6,7,8-tetrahydroquinoline; 5,6α-Epoxy-5,6,7,8-tetrahydroquinoline; 5,7-Epoxy-5,6,7,8-tetrahydroquinoline; Quinoline, 5,6-epoxy-5,6,7,8-tetrahydro-; 1-Aza-bicyclo[4.1.0]hepta-2,4-diene; 5,6-Epoxy-1-azanorbornadiene
EINECS	Contact for details

Quality Control

Our 5,6-Epoxy5,6,7,8-Tetrahydroquinoline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The epoxide functionality may be sensitive to moisture and strong acids/bases; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.