Description

(+-)-5,6-Epoxy-5,6-Dihydroquinoline CAS NO 130536-37-7 is a high-purity, versatile epoxide derivative of quinoline, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its strained oxirane ring and fused aromatic system make it a valuable precursor for constructing complex nitrogen-containing heterocycles and pharmacologically active molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require complex quinoline-based architectures.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized nitrogen-oxygen chelating ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of organic semiconductors, light-emitting materials, and advanced polymers.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including ring-opening reactions and stereoselective transformations.
• Fine Chemical Production: Intermediate in the custom synthesis of dyes, flavors, and fragrances with specific quinoline backbones.

Basic Information

Product Name	(+-)-5,6-Epoxy-5,6-Dihydroquinoline
CAS No.	130536-37-7
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	5,6-Epoxy-5,6-dihydroquinoline; Quinoline 5,6-oxide; 5,6-Epoxyquinoline; 5,6-Dihydro-5,6-epoxyquinoline; (±)-5,6-Epoxy-5,6-dihydroquinoline; rac-5,6-Epoxy-5,6-dihydroquinoline; 5,6-Epoxy-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our (+-)-5,6-Epoxy-5,6-Dihydroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.