Description

Benzenemethanamine, 3-Chloro-4-Fluoro-α,α-Dimethyl- is a high-purity, halogenated benzylamine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated and sterically hindered amine functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the chloro-fluoro substitution pattern contributes to biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral auxiliaries and specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers, dyes, and photoactive materials due to its aromatic amine core and halogen substituents.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	Benzenemethanamine, 3-Chloro-4-Fluoro-α,α-Dimethyl-
CAS No.	130416-43-2
Molecular Formula	C9H11ClFN
Molecular Weight	187.64 g/mol
Synonyms	3-Chloro-4-fluoro-α,α-dimethylbenzylamine; 1-(3-Chloro-4-fluorophenyl)-2-methylpropan-2-amine; (3-Chloro-4-fluorophenyl)(1,1-dimethylethyl)amine; α,α-Dimethyl-3-chloro-4-fluorobenzylamine; 3-Chloro-4-fluoro-α,α-dimethylbenzenemethanamine; 2-Methyl-1-(3-chloro-4-fluorophenyl)propan-2-amine
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, 3-Chloro-4-Fluoro-α,α-Dimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.