Description

3-Chloro-1-[Tris(1-Methylethyl)Silyl]-1H-Pyrrole is a specialized organosilicon-protected pyrrole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the silyl protecting group, which shields the reactive pyrrole nitrogen, enabling precise functionalization at other positions for the construction of complex heterocyclic systems. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development and agrochemical innovation, where it facilitates the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex nitrogen-containing heterocycles for potential drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Building block for developing novel pesticides and herbicides with tailored biological activity.
• Material Science Research: Used in the creation of functionalized polymers and advanced organic electronic materials.
• Organic Synthesis Reagent: Enables regioselective electrophilic substitution reactions on the pyrrole ring in multi-step synthetic routes.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-donor ligands used in transition metal catalysis.

Basic Information

Item	Details
Product Name	3-Chloro-1-[Tris(1-Methylethyl)Silyl]-1H-Pyrrole
CAS No.	130408-83-2
Molecular Formula	C13H24ClNSi
Molecular Weight	257.87 g/mol
Synonyms	3-Chloro-1-(triisopropylsilyl)-1H-pyrrole; 1H-Pyrrole, 3-chloro-1-[tris(1-methylethyl)silyl]-; 3-Chloro-1-triisopropylsilylpyrrole; N-Triisopropylsilyl-3-chloropyrrole; TIPS-3-chloropyrrole; 3-Chloro-1-(TIPS)-1H-pyrrole; 3-Chloro-N-(triisopropylsilyl)pyrrole
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-1-[Tris(1-Methylethyl)Silyl]-1H-Pyrrole adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and GC analysis, to verify identity and assay. A detailed Certificate of Analysis (COA) documenting purity, impurities, and physical properties is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.