Description

3-(2,5-Difluorophenyl)Propionic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing the difluorophenyl moiety, which can significantly alter the physicochemical and metabolic properties of target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorophenyl group enhances bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronic Materials: Employed in the synthesis of novel organic semiconductors and electron-transport materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on fluoroorganic chemistry and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, including dyes, pigments, and advanced polymers.

Basic Information

Product Name	3-(2,5-Difluorophenyl)Propionic Acid
CAS No.	130408-15-0
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,5-Difluorohydrocinnamic Acid; 3-(2,5-Difluorophenyl)propanoic Acid; β-(2,5-Difluorophenyl)propionic Acid; (2,5-Difluorophenyl)propionic Acid; 130408-15-0; 3-(2,5-Difluorophenyl)propanoate; 2,5-Difluoro-β-phenylpropionic Acid
EINECS	Contact for details

Quality Control

Our 3-(2,5-Difluorophenyl)Propionic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.