Description

Ethanone, 1-(5-Hydroxy-1,3-Cyclohexadien-1-Yl)-, (R)- (9Ci) is a chiral, hydroxylated cyclohexadienone derivative, a specialized intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring a reactive enone system adjacent to a stereogenic center, makes it a valuable building block for constructing complex, optically active molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in stereoselective synthesis.
• Asymmetric Catalysis: Serves as a precursor for the development of chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.
• Academic & Industrial Research: Used as a model compound or starting material in methodological studies exploring new organic reactions and synthetic pathways.
• Flavor & Fragrance Precursor: Potential intermediate in the synthesis of complex odorants and flavoring agents due to its functionalized cyclic structure.
• Material Science Research: Investigated as a monomer or functional component in the development of novel polymeric materials with specific optical properties.

Basic Information

Product Name	Ethanone, 1-(5-Hydroxy-1,3-Cyclohexadien-1-Yl)-, (R)- (9Ci)
CAS No.	130384-72-4
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	(R)-1-(5-Hydroxy-1,3-cyclohexadien-1-yl)ethanone; (R)-5-Hydroxy-1-acetyl-1,3-cyclohexadiene; 1-(5-Hydroxy-1,3-cyclohexadien-1-yl)ethanone, (R)-; (R)-5-Hydroxy-1-acetylcyclohexa-1,3-diene; 130384-72-4; (R)-1-Acetyl-5-hydroxy-1,3-cyclohexadiene
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-(5-Hydroxy-1,3-Cyclohexadien-1-Yl)-, (R)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment. We support cGMP-compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; minimize exposure to air and ambient light during handling. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or pale yellow liquid/oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.