Description

Propanoic Acid, 3-Bromo-3,3-Difluoro- is a high-value fluorinated and brominated organic acid building block, essential for introducing the difluoromethyl and bromo functional groups into target molecules. Its unique structure makes it a critical intermediate for synthesizing advanced compounds with tailored properties. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications in drug discovery, crop protection, and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring difluoromethyl motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms enhance biological activity and environmental persistence.
• Organic Synthesis Reagent: Serves as a versatile electrophile or precursor for further functionalization (e.g., via coupling reactions) in complex molecule construction within R&D laboratories.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials where fluorinated segments are required for specific thermal, chemical, or surface properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes used in mechanistic studies and diagnostic agent development.

Basic Information

Product Name	Propanoic Acid, 3-Bromo-3,3-Difluoro-
CAS No.	130312-65-1
Molecular Formula	C₃H₃BrF₂O₂
Molecular Weight	188.96 g/mol
Synonyms	3-Bromo-3,3-difluoropropanoic Acid; 3,3-Difluoro-3-bromopropanoic Acid; 2-Bromo-2,2-difluoroacetic Acid, Ethyl Ester (related); Bromodifluoropropionic Acid; α-Bromo-α,α-difluoropropionic Acid; (Bromodifluoromethyl)acetic Acid; 130312-65-1; Propanoic acid, 3-bromo-3,3-difluoro-
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 3-Bromo-3,3-Difluoro- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediate production where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, oxidizing agents, and reducing agents. Due to its nature as a strong acid/organic solvent, containers must be kept tightly sealed and constructed of compatible materials (e.g., PTFE, glass). Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.