Description

2-(Benzyloxy)-1,3-Dibromo-5-Fluorobenzene is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique substitution pattern, offering reactive bromine and fluorine sites for selective cross-coupling and functionalization reactions under controlled conditions. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated and brominated aromatic cores for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom can improve lipophilicity and target binding.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed to synthesize complex chelating ligands or organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns in fine chemical production.
• Academic & Industrial R&D: Utilized in exploratory chemistry for method development and creating novel chemical entities in research laboratories.

Basic Information

Product Name	2-(Benzyloxy)-1,3-Dibromo-5-Fluorobenzene
CAS No.	130046-78-5
Molecular Formula	C₁₃H₉Br₂FO
Molecular Weight	375.01 g/mol
Synonyms	1,3-Dibromo-5-fluoro-2-(phenylmethoxy)benzene; 5-Fluoro-1,3-dibromo-2-(benzyloxy)benzene; Benzene, 1,3-dibromo-5-fluoro-2-(phenylmethoxy)-; 2-Benzyloxy-1,3-dibromo-5-fluorobenzene; 1,3-Dibromo-2-benzyloxy-5-fluorobenzene; 5-Fluoro-2-benzyloxy-1,3-dibromobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-(Benzyloxy)-1,3-Dibromo-5-Fluorobenzene is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure compliance with industry standards for fine chemical intermediates. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.