Description

(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthalenechloro(p-Cymene)Ruthenium Chloride is a high-purity, chiral ruthenium complex widely recognized as a highly efficient and enantioselective catalyst. This compound matters for its critical role in facilitating asymmetric hydrogenation and other transition metal-catalyzed reactions, enabling the synthesis of complex chiral molecules with high optical purity. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and reproducible catalytic performance for creating high-value enantiopure intermediates and active ingredients.

Application

• Asymmetric Hydrogenation Catalyst: A premier catalyst for the enantioselective reduction of functionalized olefins, ketones, and imines, a key step in pharmaceutical synthesis.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Manufacturing: Enables the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Production: Applied in the creation of complex chiral molecules used as advanced intermediates, flavors, and fragrances.
• Academic and Industrial R&D: A valuable tool for methodology development in organic synthesis and catalysis research within university and corporate laboratories.
• Process Chemistry Optimization: Employed for scaling up asymmetric transformations from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthalenechloro(p-Cymene)Ruthenium Chloride
CAS No.	130004-33-0
Molecular Formula	C54H46Cl2P2Ru
Molecular Weight	932.86 g/mol
Synonyms	(R)-RuCl(p-cymene)(BINAP) Chloride; (R)-[RuCl(p-cymene)(BINAP)]Cl; (R)-BINAP-Ru(p-cymene)Cl Chloride; (R)-(+)-[RuCl(η6-p-cymene)((R)-BINAP)]Cl; Ruthenium, chloro[(1,2,3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene][(1R)-1,1'-binaphthalene-2,2'-diylbis[diphenylphosphine]]-, chloride (1:1); (R)-Ru(BINAP)(p-cymene)Cl2; (R)-RuCl2(p-cymene)(BINAP)
EINECS	Contact for details

Quality Control

Our (R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthalenechloro(p-Cymene)Ruthenium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for catalytic applications. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C to maintain stability and catalytic activity. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Solubility	Soluble in dichloromethane, chloroform; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.