Description

1,1'-Biphenyl, 2-[(Trifluoromethyl)Thio]- is a specialized organosulfur and organofluorine compound that serves as a high-value synthetic intermediate. Its unique structure, combining a biphenyl core with a trifluoromethylthio (-SCF₃) group, makes it a critical building block for introducing lipophilicity and metabolic stability into target molecules. This compound is essential for R&D and production in advanced sectors such as pharmaceutical discovery and agrochemical development, where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing compounds with enhanced bioavailability and receptor binding affinity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the -SCF₃ group can improve pesticidal activity and environmental persistence.
• Material Science Research: Serves as a precursor for advanced organic electronic materials, including charge-transport layers and luminescent compounds.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis in asymmetric synthesis and cross-coupling reactions.
• Fluorine Chemistry Studies: A valuable reagent for investigating the properties and reactivities of sulfur-containing fluorinated groups in synthetic pathways.

Basic Information

Product Name	1,1'-Biphenyl, 2-[(Trifluoromethyl)Thio]-
CAS No.	129922-51-6
Molecular Formula	C₁₃H₉F₃S
Molecular Weight	254.27 g/mol
Synonyms	2-[(Trifluoromethyl)thio]-1,1'-biphenyl; 2-(Trifluoromethylthio)biphenyl; [1,1'-Biphenyl]-2-yl(trifluoromethyl)sulfane; o-(Trifluoromethylthio)biphenyl; 2-Biphenylyl trifluoromethyl sulfide; (2-Phenylphenyl) trifluoromethyl sulfide; Biphenyl-2-yl trifluoromethyl sulfide
EINECS	Contact for details

Quality Control

Our production of 1,1'-Biphenyl, 2-[(Trifluoromethyl)Thio]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot undergoes comprehensive analysis, including chromatographic purity assessment and structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.