Description

2-[(Trifluoromethyl)Sulfinyl]-1,1'-Biphenyl is a specialized organosulfur compound featuring a biphenyl core substituted with a trifluoromethylsulfinyl group. This unique structure makes it a valuable high-purity intermediate in advanced chemical synthesis, particularly for the development of novel active ingredients. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the introduction of a sulfinyl moiety for biological activity or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral sulfoxide ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique electronic or surface properties.
• Organic Synthesis Reagent: Employed in research laboratories for constructing complex aromatic and heterocyclic systems via cross-coupling or functional group transformation reactions.

Basic Information

Product Name	2-[(Trifluoromethyl)Sulfinyl]-1,1'-Biphenyl
CAS No.	129922-49-2
Molecular Formula	C₁₃H₉F₃OS
Molecular Weight	270.27 g/mol
Synonyms	2-[(Trifluoromethyl)sulfinyl]biphenyl; [1,1'-Biphenyl]-2-yl(trifluoromethyl)sulfoxide; 2-(Trifluoromethylsulfinyl)biphenyl; α,α,α-Trifluoro-2-phenylbenzenemethanesulfinoxide; (2-Phenylphenyl)(trifluoromethyl)sulfoxide
EINECS	Contact for details

Quality Control

We supply high-purity grades of 2-[(Trifluoromethyl)Sulfinyl]-1,1'-Biphenyl suitable for demanding R&D and scale-up applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by HPLC, GC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.