Description

Phenyl 4,6-Di-o-Dimethyl-tert-Butylsilyl-2,3-Dideoxy-α-D-Erythro-H Ex-2-Enopyranoside is a sophisticated, organosilicon-protected carbohydrate derivative, specifically designed as a key synthetic intermediate. Its primary value lies in enabling precise stereochemical control and selective deprotection strategies in complex organic syntheses. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the development of novel nucleoside analogs, antiviral agents, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of modified nucleosides and carbohydrate-based therapeutics.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Glycochemistry: Serves as a protected glycosyl donor or acceptor in the stereoselective construction of complex oligosaccharides and glycoconjugates.
• Process Chemistry: Enables scalable, high-yield synthetic routes due to the stability imparted by the tert-butyldimethylsilyl (TBDMS) protecting groups.
• Chemical Biology Probe Development: Utilized to create labeled or modified sugars for studying biological recognition and metabolic pathways.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals requiring specific chiral centers and functional group manipulation.

Basic Information

Product Name	Phenyl 4,6-Di-o-Dimethyl-tert-Butylsilyl-2,3-Dideoxy-α-D-Erythro-H Ex-2-Enopyranoside
CAS No.	129889-15-2
Molecular Formula	C24H40O4Si2
Molecular Weight	448.74 g/mol
Synonyms	Phenyl 4,6-O-bis(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside; 4,6-O-Bis-TBDMS Protected Phenyl Glycal; Phenyl 4,6-di-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside; α-D-Phenyl Glycal 4,6-bis-TBDMS Ether; 2,3-Dideoxy-α-D-erythro-hex-2-enopyranoside, 4,6-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-, phenyl-; TBDMS-protected phenyl glycal; Phenyl 4,6-di-O-TBDMS-glycal
EINECS	Contact for details

Quality Control

Every batch of Phenyl 4,6-Di-o-Dimethyl-tert-Butylsilyl-2,3-Dideoxy-α-D-Erythro-H Ex-2-Enopyranoside is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.