Description

4-Chloro-2-(4-Morpholino)-5-Thiazolecarboxaldehyde is a versatile and high-value heterocyclic building block, primarily used in advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both an electrophilic chloro substituent and a reactive aldehyde group, which allows for sequential and diverse derivatization. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiazole core's bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Ligand and Catalyst Development: The morpholino and aldehyde groups make it useful for constructing novel chelating ligands and organocatalysts.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Chloro-2-(4-Morpholino)-5-Thiazolecarboxaldehyde
CAS No.	129880-84-8
Molecular Formula	C8H9ClN2O2S
Molecular Weight	232.68 g/mol
Synonyms	4-Chloro-2-morpholin-4-yl-1,3-thiazole-5-carbaldehyde; 4-Chloro-2-(morpholin-4-yl)-1,3-thiazole-5-carboxaldehyde; 2-Morpholino-4-chloro-5-thiazolecarboxaldehyde; 4-Chloro-2-morpholino-5-formylthiazole; 5-Formyl-4-chloro-2-morpholinothiazole; 129880-84-8; 4-Chloro-2-morpholinothiazole-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(4-Morpholino)-5-Thiazolecarboxaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.