Description

3-Chloro-4-Trifluoromethoxy Acetophenone is a high-value fluorinated aromatic ketone intermediate. This compound matters for its role as a versatile building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development teams in the fine chemical, pharmaceutical, and crop protection industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and as a precursor for heterocyclic compounds in research and development.
• Material Science Research: Investigated for the creation of novel polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	3-Chloro-4-Trifluoromethoxy Acetophenone
CAS No.	129604-27-9
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	1-[3-Chloro-4-(trifluoromethoxy)phenyl]ethan-1-one; 3-Chloro-4-(trifluoromethoxy)acetophenone; 3-Chloro-α,α,α-trifluoro-p-methoxyacetophenone; 3-Chloro-4-trifluoromethoxyacetophenone; 3-Chloro-4-trifluoromethoxy phenyl methyl ketone; 3-Chloro-4-(trifluoromethoxy)phenyl methyl ketone; 3-Chloro-4-trifluoromethoxyacetylbenzene
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Trifluoromethoxy Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.