Description

Ethanone, 1-[3,4-Bis(trifluoromethyl)phenyl]- is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity of the carbonyl group combined with the strong electron-withdrawing and lipophilic properties imparted by the bis(trifluoromethyl)phenyl moiety. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology, where the trifluoromethyl groups improve membrane permeability and metabolic resistance.
• Agrochemical Active Ingredient Synthesis: Used in constructing advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to weatherfastness, pesticidal activity, and selective action.
• Liquid Crystal & OLED Material Development: Serves as a building block for fluorinated components in electronic display materials, contributing to desired dielectric anisotropy, thermal stability, and luminescent properties.
• Polymer & Specialty Chemical Modification: Incorporated into polymer backbones or as a side-chain modifier to create materials with specific chemical resistance, low surface energy, or unique optical characteristics.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for studying novel coupling reactions, carbonyl chemistry, and as a ligand precursor in organometallic catalysis.

Basic Information

Product Name	Ethanone, 1-[3,4-Bis(trifluoromethyl)phenyl]-
CAS No.	129604-25-7
Molecular Formula	C10H5F6O
Molecular Weight	270.14 g/mol
Synonyms	1-[3,4-Bis(trifluoromethyl)phenyl]ethanone; 3',4'-Bis(trifluoromethyl)acetophenone; 3,4-Bis(trifluoromethyl)acetophenone; 1-Acetyl-3,4-bis(trifluoromethyl)benzene; α,α,α,α',α',α'-Hexafluoro-3,4-dimethylacetophenone; 3,4-Di(trifluoromethyl)acetophenone; 3,4-Bis(trifluoromethyl)phenyl methyl ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[3,4-Bis(trifluoromethyl)phenyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.