Description

(S)-(-)-2-o-Benzylglycerinaldehyde is a high-purity chiral aldehyde building block of significant importance in asymmetric synthesis. Its primary value lies in its role as a versatile precursor for the synthesis of complex, biologically active molecules, enabling the construction of specific stereocenters with high enantiomeric purity. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), natural product analogs, and novel ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of β-blockers, antiviral agents, and other therapeutic compounds.
• Natural Product Synthesis: Used in the total synthesis of complex natural products requiring specific (S)-configured glyceraldehyde derivatives.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in transition metal catalysis and organocatalysis.
• Peptidomimetics and Amino Acid Derivatives: Employed in the preparation of non-natural amino acids and peptide analogs with enhanced stability or activity.
• Chemical Biology Probes: Useful for creating tagged or modified sugar analogs and other probes for studying biological mechanisms.
• Fine Chemical Research: A valuable starting material in academic and industrial R&D for exploring new asymmetric transformations and reaction pathways.

Basic Information

Product Name	(S)-(-)-2-o-Benzylglycerinaldehyde
CAS No.	129492-58-6
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	(S)-2-O-Benzylglyceraldehyde; (S)-(-)-2-O-Benzylglyceraldehyde; (S)-2-Benzyloxy-3-hydroxypropanal; (S)-3-Hydroxy-2-(phenylmethoxy)propanal; (S)-2-O-Benzylglycerinal; Benzyl (S)-glyceraldehyde acetal; (S)-2-O-Bn-Glyceraldehyde
EINECS	Contact for details

Quality Control

Every batch of (S)-(-)-2-o-Benzylglycerinaldehyde is produced and tested under strict quality management protocols to ensure consistency and high enantiomeric purity. Our products undergo rigorous quality testing, including chiral HPLC analysis, to ensure compliance with research and process development standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. For long-term storage, keep the material in a cool, dry, and well-ventilated area away from incompatible substances.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.