Description

Ethanone, 1-(4Bs,8As)-4B,5,6,7,8,8A,9,10-Octahydro-2-Hydroxy-4B,8,8-Trimethyl-1-(1-Methylethyl)-3-Phenanthrenyl- is a complex, high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral building block in the development of complex molecular architectures, particularly in the pharmaceutical sector. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of steroidal or terpenoid-based active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents with specific stereochemical requirements.
• Fine Chemical Production: Serves as a specialized building block for synthesizing complex fragrance and flavor compounds.
• Academic & Industrial Research: A valuable reagent for methodological studies in asymmetric synthesis and natural product total synthesis.
• Material Science Research: Potential monomer or precursor for developing novel polymers with specific optical or structural properties.

Basic Information

Product Name	Ethanone, 1-(4Bs,8As)-4B,5,6,7,8,8A,9,10-Octahydro-2-Hydroxy-4B,8,8-Trimethyl-1-(1-Methylethyl)-3-Phenanthrenyl-
CAS No.	129456-85-5
Molecular Formula	C22H32O2
Molecular Weight	328.49 g/mol
Synonyms	1-[(4bS,8aS)-4b,5,6,7,8,8a,9,10-Octahydro-2-hydroxy-4b,8,8-trimethyl-1-(propan-2-yl)phenanthren-3-yl]ethan-1-one; 3-Acetyl-2-hydroxy-4b,8,8-trimethyl-1-isopropyl-4b,5,6,7,8,8a,9,10-octahydrophenanthrene; Trimethylisopropyloctahydrophenanthrenyl Ethanone; (4bS,8aS)-3-Acetyl-1-isopropyl-2-hydroxy-4b,8,8-trimethyl-4b,5,6,7,8,8a,9,10-octahydrophenanthrene; Chiral Octahydrophenanthrene Derivative; Advanced Steroid-like Intermediate.
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(4Bs,8As)-4B,5,6,7,8,8A,9,10-Octahydro-2-Hydroxy-4B,8,8-Trimethyl-1-(1-Methylethyl)-3-Phenanthrenyl- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.