Description

1,2-Dioleoyl-3-Succinylglycerol is a synthetic glyceride derivative, specifically a succinylated triglyceride analog. This compound is valued for its unique amphiphilic structure, which provides excellent emulsifying and solubilizing properties. It is primarily utilized in advanced pharmaceutical formulations, cosmetic products, and as a specialized intermediate in lipid-based drug delivery systems for enhancing bioavailability.

Application

• Pharmaceutical Excipient: Key component in lipid-based drug delivery systems (LBDDS) such as self-emulsifying drug delivery systems (SEDDS) and solid lipid nanoparticles (SLNs) to improve the solubility and absorption of poorly water-soluble active pharmaceutical ingredients (APIs).
• Cosmetic Ingredient: Acts as a high-performance emollient and stabilizer in creams, lotions, and sunscreens, providing texture enhancement and improved skin feel.
• Biochemical Research: Used as a substrate or model compound in enzymatic studies, particularly those involving lipases and esterases, and in membrane biophysics research.
• Nutraceutical Carrier: Employed in the formulation of advanced nutraceuticals and fat-soluble vitamins (A, D, E, K) to enhance their stability and bioavailability.
• Specialty Surfactant: Serves as a non-ionic surfactant or co-emulsifier in specialized industrial applications requiring biocompatible and biodegradable properties.

Basic Information

Product Name	1,2-Dioleoyl-3-Succinylglycerol
CAS No.	129445-40-5
Molecular Formula	C45H80O8
Molecular Weight	749.1 g/mol
Synonyms	1,2-Dioleoyl-3-succinyl-rac-glycerol; Succinyl diolein; 3-Succinyl-1,2-dioleoylglycerol; Glycerol 1,2-dioleate 3-succinate; Dioleoyl succinylglycerol; Succinylated triglyceride; Lipid SA-2; DOSG
EINECS	Contact for details

Quality Control

Our 1,2-Dioleoyl-3-Succinylglycerol is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and cosmetic research and development. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Specifications can be aligned with cGMP guidelines for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and hydrolysis. Keep away from strong bases and organic solvents. The storage area should be cool, dry, and well-ventilated.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Acid Value	≤ 5.0 mg KOH/g
Peroxide Value	≤ 10.0 meq/kg
Water Content (KF)	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.