Description

Megalomicin is a macrolide antibiotic complex, primarily known for its potent antibacterial activity against Gram-positive bacteria and certain Gram-negative organisms. Its significance lies in its role as a key intermediate in pharmaceutical research and development, particularly for studying antibiotic mechanisms and synthesizing novel derivatives. This product is essential for R&D laboratories, academic institutions, and pharmaceutical companies focused on antimicrobial discovery and development. Megalomicin CAS NO 129428-69-9 is supplied as a high-purity reference standard to ensure reliable and reproducible experimental results.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and starting material for the synthesis and study of novel macrolide antibiotics.
• Antimicrobial Mechanism Studies: Used in biochemical and microbiological assays to investigate bacterial protein synthesis inhibition and resistance mechanisms.
• Analytical Standard: Employed as a certified reference material in HPLC, LC-MS, and other analytical methods for quality control and method validation.
• Academic Research: Utilized in university and institutional labs for teaching and advanced research in medicinal chemistry and microbiology.
• Bioconjugation & Derivative Synthesis: Acts as a scaffold for creating targeted antibiotic conjugates and exploring structure-activity relationships (SAR).

Basic Information

Product Name	Megalomicin
CAS No.	129428-69-9
Molecular Formula	C45H77NO17
Molecular Weight	904.1 g/mol
Synonyms	Megalomicin A; Antibiotic XK-41-2; Megalomicin complex; 6-Deoxy-13-[(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)oxy]-3-{[(4,6-dideoxy-3-C-methyl-2-O-methyl-α-L-manno-hexopyranosyl)oxy]methyl}-3,4,5,11,12,13,15,16-octahydro-14,16-dihydroxy-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-7,11,15-triene-4-acetic acid; XK 41-2; Antibiotic XK 41-2
EINECS	Contact for details

Quality Control

Our Megalomicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR and NMR, purity assessment by HPLC, and specific tests for related substances and residual solvents, to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.