Description

2''-Chloro-3''-(Trifluoromethyl)Acetophenone is a high-value, multi-functional aromatic ketone building block characterized by its chloro and trifluoromethyl substituents. This compound is essential for the synthesis of complex molecules, where its unique halogenated structure imparts critical electronic and steric properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen atoms.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a precursor for heterocyclic compounds in academic and industrial R&D laboratories.
• Fluorine Chemistry Studies: An important compound for investigating the influence of fluorine atoms on molecular properties and reactivity.

Basic Information

Item	Details
Product Name	2''-Chloro-3''-(Trifluoromethyl)Acetophenone
CAS No.	129322-82-3
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	1-(2-Chloro-3-(trifluoromethyl)phenyl)ethan-1-one; 2'-Chloro-3'-(trifluoromethyl)acetophenone; α-Chloro-α,α,α-trifluoro-m-acetophenone; 2-Chloro-3-trifluoromethylacetophenone; 1-(2-Chloro-3-(trifluoromethyl)phenyl)ethanone; m-Trifluoromethyl-o-chloroacetophenone; 2-Chloro-α,α,α-trifluoro-3-methylacetophenone
EINECS	Contact for details

Quality Control

Every batch of 2''-Chloro-3''-(Trifluoromethyl)Acetophenone is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from GC, HPLC, and NMR, to ensure identity, purity, and consistency meet your precise research or production requirements. Our commitment to traceability and reliability supports your compliance needs in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.