Description

1-(2-Chloro-4-(Trifluoromethyl)Phenyl)Ethanone is a high-purity, specialized aromatic ketone building block of significant importance in advanced organic synthesis. Its core value lies in the strategic combination of chloro and trifluoromethyl substituents on the phenyl ring, which are critical for modulating the electronic and steric properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients with enhanced potency and selectivity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of small molecule therapeutics targeting various disease pathways.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group often contributes to improved biological activity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing specialized monomers or ligands used in the development of advanced polymers and functional materials.
• Organic Electronic Materials: Investigated as a starting material for creating charge-transport or emissive materials in OLEDs and other electronic applications.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical reactions involving halogenated trifluoromethyl aromatics.
• Ligand and Catalyst Preparation: Utilized to synthesize complex organic ligands for metal catalysis or as a scaffold for catalyst development.

Basic Information

Product Name	1-(2-Chloro-4-(Trifluoromethyl)Phenyl)Ethanone
CAS No.	129322-81-2
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	2'-Chloro-4'-(trifluoromethyl)acetophenone; 2-Chloro-α,α,α-trifluoro-p-acetophenone; 1-[2-Chloro-4-(trifluoromethyl)phenyl]ethan-1-one; 2-Chloro-4-trifluoromethylacetophenone; 2-Chloro-α,α,α-trifluoro-4-acetophenone; 2-Chloro-4-(trifluoromethyl)acetophenone; Ethanone, 1-[2-chloro-4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-4-(Trifluoromethyl)Phenyl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing all test results are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.