Description

7-Amino-5-benzyl-5-azaspiro[2.4]heptane is a specialized spirocyclic amine building block of significant interest in advanced organic synthesis. Its unique fused-ring structure containing both amino and benzyl-protected amine functionalities makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require complex, bioactive amine scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for exploring new spirocyclic and polycyclic compound libraries.
• Fine Chemical Production: An intermediate in the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	7-Amino-5-benzyl-5-azaspiro[2.4]heptane
CAS No.	129306-07-6
Molecular Formula	C13H18N2
Molecular Weight	202.30 g/mol
Synonyms	5-Benzyl-5-azaspiro[2.4]heptan-7-amine; 5-Azaspiro[2.4]heptane-7-amine, 5-benzyl-; 7-Amino-5-benzyl-5-azaspiro[2.4]heptane; 129306-07-6; 5-Benzyl-5-aza-spiro[2.4]heptan-7-ylamine; Benzyl-azaspiroheptylamine; Spirocyclic benzyl amine intermediate
EINECS	Contact for details

Quality Control

Our production of 7-Amino-5-benzyl-5-azaspiro[2.4]heptane adheres to strict in-process controls to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques including HPLC, GC, and NMR for identity confirmation and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with each shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.