Description

2-Nitro-3-Hydroxy Benzonitrile is a versatile aromatic nitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern, featuring both nitro and hydroxy groups ortho to the nitrile functionality, makes it a valuable building block for constructing complex heterocyclic systems and fine chemicals. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing benzoxazole, quinazoline, or other fused heterocyclic cores.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators that require specific nitro-substituted aromatic scaffolds.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized azo dyes and organic pigments where the nitro and hydroxy groups contribute to color properties and molecular stability.
• Material Science Research: Used in academic and industrial R&D for creating novel polymers, ligands for metal-organic frameworks (MOFs), and other advanced functional materials.
• Chemical Synthesis Reagent: Serves as a starting material or reagent in multi-step organic syntheses for fine chemicals and specialty compounds.

Basic Information

Product Name	2-Nitro-3-Hydroxy Benzonitrile
CAS No.	129298-23-3
Molecular Formula	C7H4N2O3
Molecular Weight	164.12 g/mol
Synonyms	3-Hydroxy-2-nitrobenzonitrile; 2-Nitro-3-cyanophenol; Benzonitrile, 3-hydroxy-2-nitro-; 2-Nitro-3-hydroxybenzene carbonitrile; 2-Nitro-3-phenol carbonitrile; 3-Cyano-2-nitrophenol; 2-Nitro-3-cyanophenol
EINECS	Contact for details

Quality Control

Our 2-Nitro-3-Hydroxy Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each production lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via FT-IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of nitro and hydroxy functional groups, the material should be stored separately from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.