Description

Ethyl 1-Amino-3-Oxocyclobutane-1-Carboxylate is a high-purity, multifunctional cyclobutane derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a keto ester group on a strained four-membered ring, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used as a precursor in the research and production of new-generation herbicides and fungicides with novel modes of action.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for the synthesis of polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological studies and the synthesis of complex natural product analogs.
• Peptidomimetics: The constrained cyclobutane ring is used to introduce conformational rigidity into peptide analogs, enhancing their stability and biological activity.

Basic Information

Item	Detail
Product Name	Ethyl 1-Amino-3-Oxocyclobutane-1-Carboxylate
CAS No.	129287-91-8
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	1-Amino-3-oxocyclobutane-1-carboxylic acid ethyl ester; Ethyl 1-amino-3-oxocyclobutanecarboxylate; 1-Amino-3-oxocyclobutanecarboxylic Acid Ethyl Ester; 3-Oxo-1-aminocyclobutane-1-carboxylic acid ethyl ester; Amino-oxocyclobutanecarboxylate; AOCB Ester; Cyclobutane-1-amino-3-one-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 1-Amino-3-Oxocyclobutane-1-Carboxylate is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for research and fine chemical intermediates. A detailed Certificate of Analysis (COA), including purity assay and impurity profile, is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.