Description

Benzamide, N,N'-[[2,2,2-Trifluoro-1-(Trifluoromethyl)Ethylidene]Bis(6-Hydroxy-3,1-Phenylene)]Bis[4-Amino- is a high-purity, complex aromatic amide derivative characterized by its unique trifluoromethyl-substituted ethylidene bridge and multiple functional groups. This compound matters as a critical advanced pharmaceutical intermediate and a versatile building block for synthesizing sophisticated molecules with tailored properties. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to incorporate fluorinated motifs for enhanced bioactivity, metabolic stability, or material performance.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anticancer drugs where the fluorinated segment is crucial.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and pesticides, leveraging the fluorine atoms to improve lipophilicity, membrane permeability, and environmental persistence.
• Specialty Polymer Synthesis: Acts as a monomer or cross-linking agent for creating high-performance polymers, such as polyimides or polyamides, with exceptional thermal stability, chemical resistance, and low dielectric constants for electronics.
• Ligand & Catalyst Development: The amino and phenolic hydroxyl groups make it a valuable scaffold for designing chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system and electron-withdrawing fluorinated groups.
• Fluorine Chemistry Studies: A valuable reference compound for academic and industrial research focused on understanding the synthesis and reactivity of highly fluorinated organic molecules.

Basic Information

Product Name	Benzamide, N,N'-[[2,2,2-Trifluoro-1-(Trifluoromethyl)Ethylidene]Bis(6-Hydroxy-3,1-Phenylene)]Bis[4-Amino-
CAS No.	129197-38-2
Molecular Formula	C29H20F6N4O4
Molecular Weight	602.49 g/mol
Synonyms	4,4'-(Hexafluoroisopropylidene)bis(2-aminophenol) bis(4-aminobenzamide) derivative; N,N'-[2,2,2-Trifluoro-1-(trifluoromethyl)ethylidene]bis[6-hydroxy-1,3-phenylene]bis(4-aminobenzamide); 1,3-Bis(4-aminobenzamido)-5-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]benzene; Bis(4-aminobenzoyl) derivative of 4,4'-(Hexafluoro-2,2-propanediyl)dianiline analogue; 4-Aminobenzamide, N,N'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis(6-hydroxy-1,3-phenylene) ester; HFIP-Bis(ABA); Aromatic tetrafunctional amide monomer
EINECS	Contact for details

Quality Control

Our Benzamide, N,N'-[[2,2,2-Trifluoro-1-(Trifluoromethyl)Ethylidene]Bis(6-Hydroxy-3,1-Phenylene)]Bis[4-Amino- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.