Description

1-Propanone, 2-Fluoro-1-[4-(2-Methylpropyl)Phenyl]- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials, where the introduction of fluorine atoms is critical for modulating biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers within the pharmaceutical, agrochemical, and material science industries seeking to incorporate unique fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances metabolic stability and bioactivity.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Advanced Polymer Synthesis: Employed to create monomers for specialty polymers with tailored thermal, optical, and surface properties.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological mechanisms and diagnostics.
• Cross-Coupling Reactions: Functions as an electrophilic coupling partner in palladium-catalyzed reactions for constructing complex biaryl systems.

Basic Information

Product Name	1-Propanone, 2-Fluoro-1-[4-(2-Methylpropyl)Phenyl]- (9Ci)
CAS No.	129159-24-6
Molecular Formula	C13H17FO
Molecular Weight	208.27 g/mol
Synonyms	2-Fluoro-1-[4-(2-methylpropyl)phenyl]propan-1-one; 2-Fluoro-1-[4-(isobutyl)phenyl]propan-1-one; 2-Fluoro-1-(4-isobutylphenyl)propan-1-one; α-Fluoro-4-isobutylpropiophenone; 4-Isobutyl-2-fluoropropiophenone; 129159-24-6 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 1-Propanone, 2-Fluoro-1-[4-(2-Methylpropyl)Phenyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.