Description

1H,3H-Pyrrolo[1,2-C][1,3,2]Oxazaborole, 1-Butyltetrahydro-3,3-Diphenyl-, (S)- is a high-value, chiral organoboron compound that serves as a critical intermediate and catalyst in advanced synthetic chemistry. Its significance lies in its role as a highly effective chiral catalyst or ligand for enantioselective transformations, enabling the production of optically pure pharmaceutical and fine chemical intermediates. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control in their synthesis processes.

Application

• As a chiral catalyst in asymmetric synthesis, including reductions and carbon-carbon bond-forming reactions.
• As a key ligand for transition metal complexes used in enantioselective catalysis.
• As a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• In the research and development of novel agrochemicals and performance chemicals where chirality impacts biological activity.
• For process development and scale-up in fine chemical manufacturing.
• In academic and industrial research focused on organoboron chemistry and new catalytic methodologies.

Basic Information

Item	Detail
Product Name	1H,3H-Pyrrolo[1,2-C][1,3,2]Oxazaborole, 1-Butyltetrahydro-3,3-Diphenyl-, (S)-
CAS No.	129145-37-5
Molecular Formula	C22H28BNO
Molecular Weight	333.28 g/mol
Synonyms	(S)-1-Butyl-3,3-diphenyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; (S)-Tetrahydro-1-butyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; (S)-1-n-Butyl-3,3-diphenyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; (S)-CBS Catalyst; (S)-Corey-Bakshi-Shibata Catalyst; (S)-Oxazaborolidine Catalyst; (S)-1-Butyl-3,3-diphenyl-1,3,2-oxazaborolidine
EINECS	Contact for details

Quality Control

Our production of this advanced chiral compound adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.